Khloe Kardashian seems like her feelings were really hurt by something Amy Schumer said as she hosted SNL this weekend. Sure, the Kardashian ladies have pretty thick skin, but it must hurt every now and then when constantly being made fun of in the media.

Amy Schumer’s blow was at Khloe Kardashian’s recent weight loss. The Keeping Up With the Kardashians star hit back via Twitter, but she did so in a much kinder way.

No need 2 tear down others just 2 make urself feel bigger. It actually makes u quite small. I'm on a healthy journey. I don't care 4the hate

— Khloé (@khloekardashian) October 11, 2015

Maybe thinking her first Tweet was a bit of a downer, Khloe Kardashian posted a second one shortly thereafter.

Let's uplift one another!!! Happy Sunday! Stay smiling!!! ??????????

— Khloé (@khloekardashian) October 11, 2015

So what was it Amy Schumer said that bothered Khloe Kardashian? It went like this.

Amy began–during her monologue–by saying the world needs more role models for little girls because, “who do they have? All they have, literally, is the Kardashians.”

“Is that a great message for little girls? A whole family of women who take the faces they were born with as like, a light suggestion?” Schumer said.

“We used to have Khloé. Khloé was ours, right?” Schumer continued. “Whenever there’s a group of women, you identify with one of them, right? But Khloé–she lost half her body weight.”

She went on to say that Khloe Kardashian “lost a Kendall,” referring to her younger sister Kendall Jenner.

Khloe Kardashian recently shared she has lost 35 pounds.

No time for hate! Khloé Kardashian says she's on healthy journey after Amy Schumer mocks her http://t.co/N49YMLPk6C pic.twitter.com/fQjmrZRgAY

— E! Online UK (@EOnlineUK) October 12, 2015

Do you think Khloe was simply having an off-day or did Amy Schumer’s remarks really hit a nerve?

Don’t you love how Khloe Kardashian urged people to build each other up instead of breaking them down?